The temptation is to load up the truck and head south, but this disaster is so massive it's better to work through some organization, such as your church. Here's the link to the national United Methodist relief organization:UMCOR is collaborating with FEMA and other national disaster response organizations, including the American Red Cross, Lutheran Disaster Response, Southern Baptist Disaster Relief, and the umbrella group, National Voluntary Organizations Active in Disasters (NVOAD).
Rolling Hills Ministries
And here's a Baptist link. Rolling Hills Ministries, based in Ruston, Louisiana, is an efficient and compassionate source of help. It sends teams to help with disasters.